uric acid

Sabtu, 03 Maret 2018

what causes gout




What Causes the Drop?
Causes of the Drop
History in Brief -

    It was determined that the true cause of gout is having high levels of uric acid in the blood, known as hyperuricemia.
    To combat it, monitor very closely your uric acid levels, because if allowed to increase, it also increases the risk of gout attacks or episodes of inflammation

In past centuries, it was believed that people had gout due to a viscous mood. According to ancient Western physiology, humor is 1 of the 4 bodily fluids that define the characteristics and temperament of a person. These fluids "filter out of the blood" and deposit in the joints where they cause extreme pain.
The Dangers of Having High Levels of Uric Acid

Over time, it was determined that the true cause of gout is having high levels of uric acid in the blood, known as hyperuricemia. Gout occurs due to the collapse of the metabolic process that must regulate the amount of uric acid in the blood.

Generally, uric acid dissolves in the blood and passes through the kidneys without causing damage. But when the body produces too much uric acid or does not release an adequate amount of uric acid in its urine, it accumulates and produces painful needle-shaped crystals in the joints and surrounding tissues.

To combat this situation, you should carefully monitor your uric acid levels, because if you allow them to increase, you also raise the risk of gout attacks or episodes of inflammation.
Risk Factors That Could Predispose the Drop

There are numerous risk factors that determine the chances of being diagnosed with gout. These include:

• An unhealthy diet with:

? High amounts of alcohol: alcoholic beverages increase their levels of uric acid in the blood, which causes attacks of gout.

? Foods containing high fructose corn syrup (HFCS): This ingredient, present in many beverages and current processed foods, has been shown to be linked to gout.

Having an excess of fructose in the system prevents the uric acid from being excreted, which results in an accumulation of high levels of this in the body. In fact, the inflammation often associated with gout is related to high levels of blood sugar.

In addition, fructose produces toxins and waste (and uric acid is one of them) when it is metabolized by the liver, and is linked to other health problems and chronic diseases.

? Foods rich in purine: it is a natural substance that is found in body cells and food, 1 the purine is broken down in the body and transformed into uric acid. As mentioned above, excess uric acid produces high blood levels, joint damage and pain.

Some examples of foods rich in purine include organs and red meat, seafood, 2 anchovies, herring, mushrooms, asparagus, cauliflower, red beans, lentils, spinach and peas, to name a few.1 If you have gout or have signs of this disease, avoid these foods or consume them in moderation.

• Obese or overweight: if you are obese or overweight, you are also more likely to be affected by gout. 4 Gout attacks or episodes of inflammation can be exacerbated by certain factors, and excess body weight plays a role in this. What's the score? An irritation of the nerve endings, which were already sensitive.

The inflammation experienced by patients suffering from gout is also associated with another disease: the metabolic syndrome. This syndrome is produced when the metabolism of your body does not work properly, which causes several biochemical and physiological abnormalities. 5 The common characteristics of this disorder are obesity, hypertension, and impaired glucose and insulin metabolism.


A key factor in the onset of the metabolic syndrome is having high levels of uric acid in the blood, so it is not surprising that medical data and case series studies have shown that patients suffering from gout had a high prevalence of metabolic syndrome. 6

• Existing medical problems: people with diabetes, heart disease, and / or high cholesterol and blood pressure, and who underwent gastric bypass surgery, have an increased risk of this disease. 7

• Medications: taking this type of medication may predispose you to the likelihood of a diagnosis of gout:

? Diuretic medications or "water pills" are usually needed for high blood pressure 8

? Low doses of aspirin 9

? Immunosuppressants (drugs that decrease the strength of the body's immune system) 10 such as cyclosporine (Neoral and Sandimmune) and tacrolimus (Prograf) 11

• Genetics: although it is a minor factor, a child who has one or both parents who suffer from gout, could be diagnosed later with the disease.


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